Lymphatic System: Lymph Vessels, Lymph Nodes, and Lymph
Circulation:
Lymph Vessels
Lymphatic vessels are a network of thin-walled tubes that
transport lymphatic fluid, or lymph, throughout the body. They are similar in
structure to veins but have thinner walls and contain valves to prevent the
backward flow of lymph.
- Function:
- Collect
excess fluid from tissues
- Transport
immune cells and antibodies
- Absorb
fats from the digestive system
- Types:
- Lymphatic
capillaries: Tiny vessels that collect fluid from tissues. These
capillaries have a unique structure with one-way valves that allow fluid
to enter but not exit. This helps to ensure the unidirectional flow of
lymph.
- Lymphatic
collecting vessels: Larger vessels that carry lymph from lymphatic
capillaries to lymph nodes. These vessels have a more muscular wall and
contain valves to prevent the backward flow of lymph.
- Lymphatic
ducts: The largest lymphatic vessels that drain lymph back into the
bloodstream. There are two main lymphatic ducts: the thoracic duct and
the right lymphatic duct.
Lymph Nodes
Lymph nodes are small, bean-shaped organs located along
lymphatic vessels. They are an important part of the immune system.
- Function:
- Filter
lymph: Lymph nodes contain a network of lymphatic sinuses that are
filled with lymphocytes, macrophages, and other immune cells. As lymph
passes through these sinuses, foreign substances and pathogens are
filtered out.
- Produce
immune cells: Lymph nodes are a major site of production for
lymphocytes, including B cells and T cells, which are essential for
immune function.
- Store
immune cells: Lymph nodes store large numbers of immune cells,
including lymphocytes and macrophages, that can be quickly mobilized to
fight infection.
- Help
fight infection: When the body is infected, lymph nodes become
enlarged and active as they produce and store immune cells to combat the
infection.
- Structure:
Lymph nodes are surrounded by a capsule and are divided into compartments
called cortical nodules and the medulla. The cortical nodules contain a
dense concentration of lymphocytes, while the medulla contains a network
of lymphatic sinuses that are filled with macrophages and other immune
cells.
Lymph Circulation
Lymph circulation is the movement of lymph through the
lymphatic vessels and lymph nodes. It is a one-way system that begins in the
tissues and ends in the bloodstream.
- Pathway:
- Fluid
collection: Lymph is collected from tissues by lymphatic capillaries.
These capillaries have a unique structure that allows fluid to enter but
not exit.
- Transport
to lymph nodes: Lymph flows through lymphatic collecting vessels to
lymph nodes. These vessels are larger than lymphatic capillaries and
contain valves to prevent the backward flow of lymph.
- Filtration
and immune response: In lymph nodes, lymph is filtered and immune
cells are added. This helps to remove foreign substances and pathogens
from the lymph.
- Return
to bloodstream: Lymph is transported through larger lymphatic vessels
to the lymphatic ducts. The thoracic duct drains lymph from most of the
body, while the right lymphatic duct drains lymph from the right upper
quadrant of the body. These ducts empty into the subclavian veins,
returning lymph to the bloodstream.
Lymphatic Tissue: Spleen and Thymus
Spleen
- Function:
The spleen plays a crucial role in the immune system by filtering blood,
removing old red blood cells, and producing immune cells. It also stores
blood cells and helps to regulate blood volume.
- Structure:
The spleen is a bean-shaped organ located in the upper left quadrant of
the abdomen. It is divided into red pulp and white pulp. The red pulp
contains a large number of red blood cells and macrophages, while the
white pulp contains lymphocytes and other immune cells.
Thymus
- Function:
The thymus is a primary lymphoid organ that is essential for the
development of T cells, a type of immune cell that plays a crucial role in
cell-mediated immunity.
- Structure:
The thymus is located in the upper chest, behind the sternum. It is most
active during childhood and adolescence, and it gradually shrinks with
age.
The lymphatic system plays a
vital role in the immune system by helping to fight infection and maintain
fluid balance in the body.

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